Different cannabis plants are bred to contain different amounts of CBD and/or THC. The plants we know as marijuana are bred specifically to contain CBD and/or THC. However, “the form of the cannabis plant we know as hemp is bred to naturally not contain appreciable amounts of THC, which is the psychoactive compound in the plant people are after when they want a high,” explains Leslie Mendoza Temple, M.D., A.B.O.I.M., medical director of NorthShore University HealthSystem’s Integrative Medicine Program. THC-free hemp plants are referred to as ‘industrial hemp.’
In a Phase II double-blind, randomized, placebo-controlled, 5-week study of 56 rheumatoid arthritis patients with Sativex (Blake et al 2006), employed nocturnal treatment only to a maximum of 6 sprays per evening (16.2 mg THC + 15 mg CBD). In the final treatment week, morning pain on movement, morning pain at rest, DAS-28 measure of disease activity, and SF-MPQ pain at present all favored Sativex over placebo (Table 1).
In fact, the U.S. Food and Drug Administration (FDA) approved Epidiolex (a drug made with a purified form of CBD oil) in June 2018 for the treatment of seizures associated with two rare and severe forms of epilepsy in patients 2 years of age and older. These two epilepsy forms are known as Lennox-Gastaut syndrome and Dravet syndrome. Epidiolex is the first FDA-approved drug that contains a purified drug substance derived from marijuana.
While only 9 states currently have legalized recreational marijuana, as an industry weed has had a huge year of growth. This is in large part due to the increasing popularity of products that contain CBD in them. CBD, short for cannabidiol, is one of the hundreds of compounds found in the cannabis plant, and the potential it has shown in helping with pain, seizures and anxiety have made it a natural fit for medical and recreational weed alike.
Cannabis used to always spell "High" to me and hence I avoided using the products in the market for reducing anxiety and stress. When someone recommended Sera Relief CBD Oil, I gave them a try and was amazed to experience a relief from my knee arthritis and less anxiety without the feeling of being high. Its anti-oxidant supports helps me stay focused.
There has been a lot of hype recently, especially throughout the media, regarding the rising-in-popularity CBD, but still plenty of confusion may exist regarding this naturally occurring chemical’s abilities, composition and why exactly it works. Probably the two most common topical forms of CBD are oils and creams, so these are the two products we will be focusing on.
A clinical endocannabinoid deficiency has been postulated to be operative in certain treatment-resistant conditions (Russo 2004), and has received recent support in findings that anandamide levels are reduced over controls in migraineurs (Sarchielli et al 2006), that a subset of fibromyalgia patients reported significant decreased pain after THC treatment (Schley et al 2006), and the active role of the ECS in intestinal pain and motility in irritable bowel syndrome (Massa and Monory 2006) wherein anecdotal efficacy of cannabinoid treatments have also been claimed.
Everything you need to know about marijuana (cannabis) Marijuana, or cannabis, is the most commonly used illicit drug in the world. It alters the mood and affects nearly every organ in the body. With at least 120 active compounds, marijuana may have health benefits as well as risks. We describe these, addiction, and withdrawal. Learn more about cannabis here. Read now

A 2017 article published by the National Academies of Sciences, Engineering and Medicine conducted a study in which the results concluded, “In adults with chronic pain, patients who were treated with cannabis or cannabinoids are more likely to experience a clinically significant reduction in pain symptoms.” This statement is quite a massive development for the increasing of tolerance towards CBD and CBD based products.
I am 70 years old and have arthritic pain and stiffness in my hands. I work part-time for a delivery company and spend 4-5 hour shifts removing small and large packages from a belt think of Lucy and Ethel at the chocolate factory. I bought the 3000 MG tincture about two weeks. I started out with 6 drops @ 2X per day 30MG. It took the edge off of aches and pains from working and arthritic pain but increased the dose to 7 drops @ 3 times per day 52.5 MG. Although I still felt some aches and pains it decreased considerably. Today I have started 7 drops 4X per day 75 MG. I anticipate getting much better results. All-in-all I am quite pleased with the 3000 tincture oil. I feel that the oil has given me more energy to do things around the house probably because I am now experiencing much fewer aches and pains in my body and hands. By the way the reason I am taking the oil 4 times a day is because I read that the body will not absorb more than 15 MG at a time and discards any oil above that amount. It may not be true but thats my story and Im sticking to it.
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia.
In the United States, we saw the U.S. Food and Drug Administration (FDA) approve its very first cannabis-derived drug in June, saw a handful of new states give the green light to pot during midterm elections, and observed as President Trump legalized hemp and hemp-based cannabidiol (CBD) in December by signing the Farm Bill into law. CBD is the nonpsychoactive cannabinoid best known for its medical benefits. 
Mark Batterson is the bestselling author of several books, and serves as Lead Pastor of National Community Church in Washington D.C. Known as the "movie theater" church, NCC meets in cinemas throughout the DC metro area. Mark's passion, shared through his books and ministry, is to communicate the truths of the Bible in relevant ways that bring hope and purpose to people's real lives.
To be clear, there is no one specific test, scan, or anything else of the sort that you can do to determine whether or not you need CBD oil for pain. Also, since cannabis is not yet recognized by the FDA, you unfortunately can’t really go to your doctor either and have them recommend it; until marijuana is FDA-approved, it cannot be prescribed by physicians.
The CBD oil we offer has a couple different applications. You can hold a sublingual dose under the tongue for 30-60 seconds (recommended for fastest absorption), apply the oil topically to your skin (can be applied directly to a problem area or mixed with your favorite moisturizer), or blend the oil in a health-conscious smoothie. We will include further dosing instructions with the product.
My dad has severe advanced stage Dementia. Will CBD oil help him at this point? He is now refusing to eat any solid food, but will accept most drinks.In addition, he has lost a great deal of weight even though they're giving him Mega Shakes containing a full meals worth of proteins, etc. He gets at least 4 of these a day..some which he refuses. Is his Dementia too far gone for CBD oils to help him?
Preliminary research indicates that cannabidiol may reduce adverse effects of THC, particularly those causing intoxication and sedation, but only at high doses.[22] Safety studies of cannabidiol showed it is well-tolerated, but may cause tiredness, diarrhea, or changes in appetite as common adverse effects.[23] Epidiolex documentation lists sleepiness, insomnia and poor quality sleep, decreased appetite, diarrhea, and fatigue.[2]
Cannabidiol (CBD) is a naturally occurring compound found in the resinous flower of cannabis, a plant with a rich history as a medicine going back thousands of years. Today the therapeutic properties of CBD are being tested and confirmed by scientists and doctors around the world. A safe, non-addictive substance, CBD is one of more than a hundred “phytocannabinoids,” which are unique to cannabis and endow the plant with its robust therapeutic profile.
Pharmacists have since moved to metric measurements, with a drop being rounded to exactly 0.05 mL (50 μL, that is, 20 drops per milliliter) - https://en.wikipedia.org/wiki/Drop_(unit)1oz is 30 mL1000mg/30mL = 33.3 mg/mL CBD concentration20 drops * .05 mL/drop = 1mL10 drops * .05 mL/drop = .5mLyou take 33.3 mg in the morning and 16.65mg at nightI might suggest taking 50mg in the morning: 50mg / 33.3 mg/mL = 1.50 mL 30 dropstry it for a couple days and see how it helps
“I just felt good,” he adds. “But I wasn’t high at all.” Joliat’s anecdotal experience with CBD is a common one. Some informal polling suggests a lot of people today are at least vaguely familiar with cannabidiol, and have either used it themselves or know someone who has. But even some people who use it don’t seem to know exactly what it is or whether there’s any hard science out there to back up its benefits.
Generalized pain, for instance, has dozens upon dozens of high profile research and clinical studies that have been carried out in universities and laboratories around the globe. One of the most well-publicized of these studies took place back in 2008, in which results determined that “cannabinoid analgesics (pain relievers) have generally been well tolerated in clinical trials … with acceptable adverse event profiles (meaning acceptable effectiveness for practical use).
At the present time, the US Drug Enforcement Administration (DEA) lists marijuana and its cannabinoids as a Schedule I controlled substance, arguably due to THC’s psychedelic effects. This means that cannabis cannot legally be possessed, sold or prescribed. Having said that, 16 states in the United States have already CBD-specific passed laws. Hemo-derived CBD, a THC-absent variety of cannabis sativa, had been declared legal by the industry on account of the legality of hemp itself. Confusion arose, however, when the DEA issued a statement in December 2016 stating that any derivative “from any plant of the genus Cannabis” will continue to be treated as Schedule I controlled substances, lumping cannabis and hemp together. Its legality is unclear though, as in 2004 a Federal Court ruled that hemp was OK to traffic. What is clear though, is that with research on CBD and cannabis showing indisputably positive results, legalization has been picking up pace around the globe. And with CBD hemp oil already legal throughout much of the US, Australia and the EU, millions of people are already experiencing the benefits of CBD, with numbers only increasing exponentially.
The variety of cannabis known as hemp was traditionally valued primarily for its fibers with high tensile strength, making it ideal for creating rope and textiles. Hemp seeds and sprouts were eaten as a good source of high-quality protein and beneficial omega-3 fatty acids. The variety of cannabis known as marijuana was specifically cultivated for the euphoric properties of THC, which is concentrated mostly in the flower buds of the plant.
Two dermatologists I consulted with, New York-based Whitney Bowe, MD and New Jersey-based Jeanette Jacknin, MD, both agreed that CBD’s anti-aging and anti-inflammatory benefits are clinically proven. “Studies have shown that the cannabinoids like CBD in marijuana are anti-inflammatory and anti-aging and topical CBD has proven helpful for acne, eczema, and psoriasis,” Jacknin told me. “Hemp seed oil is reputed to be the most unsaturated oil derived from the plant kingdom, so it is less pore clogging but a great moisturizer for dry, cracked skin.”
Phytocannabinoid-rich hemp oil has a higher concentration of CBD compared to other cannabinoids. When ingested, CBD interacts with our body’s endocannabinoid system. This triggers the body to consume more of its own cannabinoids, which directly influences our immune system—where the majority of CBD receptors are found. This helps reduce inflammation and pain and promotes a healthier immune system.
Do you think CBD oil may be right for you? Then check out Green Roads CBD oils for the highest-quality CBD tinctures on the market! We offer CBD hemp oil tinctures in a different range of dosages, from 100mg to 3500mg per bottle, to meet your specific needs. Designed to fit into your daily routine and easy to buy online, Green Roads CBD oils were made with our customers in mind.
If you don't live in a legalized state, you can typically still get CBD-infused creams. Since there's no regulation or standardized testing, your best bet is to find trustworthy brands who use creams free of toxins but with additional pain relievers like menthol, capsaicin, lemongrass, or camphor. Try Mary's Nutritionals Muscle Freeze ($70; marysnutritionals.com) or Elixinol's CBD Rescue Balm ($40; elixinol.com).

In states where marijuana is legal or allowed for medical purposes, of course, a wider variety of potent products are available. Stores and dispensaries in states like Washington and Colorado will often stock CBD tinctures, topicals, and crystals derived from hemp's more potent sister strains; these are more effective, but are also regulated (or criminalized) in the same way as "marijuana," as a drug.   


There has actually been a substantial amount of experiments done on cannabidiol that has proved its potential healing powers. Dr. Sean McAllister, a scientist from the Pacific Medical Center in San Francisco, made an astounding discovery about CBD. McAllister has been studying cannabinoid compounds for 10 years now in search of new therapeutic interventions for various cancers. He discovered that cannabidiol is a potent inhibitor of cancer cell proliferation, metastasis, and tumor growth.
The FDA relies on applicants and scientific investigators to conduct research. Our role, as outlined in the Federal Food, Drug, and Cosmetic Act, is to review data submitted to the FDA in a marketing application to determine whether a proposed drug product meets the statutory standards for approval. Additional information concerning research on the medical use of marijuana is available from the National Institutes of Health, particularly the National Cancer Institute (NCI) and NIDA.
I have a slightly bulging disc in my back that has been causing neuropathy in my left leg for years. I’ve had several rounds of trigger point injections; see a physical therapist regularly, and lately a chiropractor as well. The next step for me would be to try an epidural pain block. Several of my other doctors are big proponents of the “inflammation as a cause of disease” theory and have really encouraged me to do things to reduce inflammation. Omega-3 fatty acids in particular help with this (as most Americans consume a poor ratio of omega-6 to omega-3 which can increase inflammation.) Hemp products contain phytocannabinoids, a substance that can help decrease pain and inflammation. This is full spectrum hemp oil derived from hemp seeds—meaning it contains all of the phytocannabinoids and not just one in particular. This is NOT CBD (cannabidiol) oil, although based on my research it likely contains low levels of CBD. CBD is the substance produced from hemp flowers (a plant with little to no THC—the substance that causes a high) (or marijuana flowers—a plant in the same family with significant THC) that is widely known to have medicinal purposes in pain relief, stopping seizures, etc.
You can rub CBD oil on your skin or drop it under your tongue; you can eat it as a sugarcoated gummy or drink it as a Goop-approved cocktail. There's evidence (some scientific, plenty anecdotal) that it helps with epileptic seizures, opioid addiction, PTSD, arthritis, anxiety, insomnia, nausea, chronic pain, and much more. If you believe the hype, CBD can do just about anything for your physical and mental health — and it won't get you high as a kite.
To be clear, there is no one specific test, scan, or anything else of the sort that you can do to determine whether or not you need CBD oil for pain. Also, since cannabis is not yet recognized by the FDA, you unfortunately can’t really go to your doctor either and have them recommend it; until marijuana is FDA-approved, it cannot be prescribed by physicians.

In a small study published in the journal JCI Insight in 2017, researchers observed that CBD may help prevent stress-related changes in blood pressure. For the study, nine healthy male volunteers took a single dose of either CBD or placebo. Compared to those given the placebo, those treated with CBD had lower blood pressure both before and after experiencing a stressful event.


Our Melt is a revolutionary pain relief CBD lotion powered by Amplifi™ Nanotechnology allowing for instant relief. We were tired of coconut oil topicals that clog pores and leave skin greasy and oily, so we developed a product with a more advanced formulation. What makes Melt™ different is that it starts with organic aloe juice, making it a water-based topical lotion. So, it glides on your skin easily and absorbs rapidly, leaving no oily or sticky residue. Then, we combined cooling menthol and warming capsicum and camphor oil for that icy hot sensation. We finished with a blend of over 20 essential oils specially engineered for pain relief.

A recent study published in The International Journal of Neurophamacologypoints to cannabidiol (CBD) as a cause of neurogenesis in the brain; specifically in the Hippocampus, an area typically associated with conscious memory and navigation. However, the researchers believe that CBD’s anxiety relief may be due to this neurogenesis in the brain. You can read our full article on the study here.
No restrictions and our always-free shipping mean for unparalleled access to some of the world’s best in organic CBD’s. In addition, we are proud to say that we are quite knowledgeable in the CBD field and CBD applications as opposed to many out there, just trying to sell a product. If you need help deciding which CBD line is best for your intended application, we are always happy to explain the options to your fullest understanding.
In a SAFEX study of Phase III double-blind RCT in 160 subjects with various symptoms of MS (Wade et al 2004), 137 patients elected to continue on Sativex after the initial study (Wade et al 2006). Rapid declines were noted in the first twelve weeks in pain VAS (N = 47) with slower sustained improvements for more than one year. During that time, there was no escalation of dose indicating an absence of tolerance to the preparation. Similarly, no withdrawal effects were noted in a subset of patients who voluntarily stopped the medicine abruptly. Upon resumption, benefits resumed at the prior established dosages.
My skin started clearing up after a week and a half (I am under lot of stress, so- pimples, acne- it WAS a problem). It is a very nutty product, I added it to my coffee and put it in the blender. Makes it nice and smooth, rich and creamy. My dog has had some kind of skin condition, I was using coconut oil she had a good coat but still had the skin problem - her hair has now grown back after two and a half weeks, and she looks forward to getting the oil in her food every morning.
Out of all the CBD products I’ve tested and used in the past few weeks, this thick green lemon-vanilla scented salve is my favorite. I massage it onto my sore red knuckles after boxing practice, and if it weren’t so expensive, I would encase my entire body in it. The cannabis sativa seed oil in this salve has antioxidant properties so that your skin can repair itself from the inside out, while the thick balm-like formula protects your skin from environmental aggressors. I would not recommend rubbing this onto your face because it’s so thick, but do whatever you want on the rest of your body—and if your feet are in need of some serious TLC in time for summer sandals weather, consider rubbing this onto your cracked heels and putting on a pair of soft socks before bed. The next morning, you’ll have baby’s feet again.
Hemp producers who sell CBD products will often use the 2014 Farm Bill to claim that it is legal. This bill includes a provision that allows for the legal cultivation of hemp provided it is used for academic agricultural research or under a state pilot program. But there is still confusion about whether the legal allowance for cultivation also includes selling it.
Extensive studies have demonstrated that many common illnesses are related to deficiencies or imbalances of specific fatty acids in the body. Symptoms are often related to a lack of Omega 3 and Omega 6 fatty acids and their derivatives, the postaglandins. Most people eating a healthful diet, one that includes a balanced ratio of essential fatty acids, also have healthy skin and a strong immune system. Yet some individuals may experience shortages in specific fatty acids or their metabolites due to dysfunctional enzyme systems or other inhibitions in their metabolic pathways caused by genetic, immune-system-related, or even environmental factors. It has been proven in several clinical studies that dietary supplementation with essential fatty acids or their metabolites (such as GLA) will often prevent or even cure these illnesses. Since hemp seed oil contains both essential fatty acids in a desirable balance while also providing two of the essential fatty acid metabolites, it is a good resource for the prevention and treatment of certain illnesses.

Cannabis used to always spell "High" to me and hence I avoided using the products in the market for reducing anxiety and stress. When someone recommended Sera Relief CBD Oil, I gave them a try and was amazed to experience a relief from my knee arthritis and less anxiety without the feeling of being high. Its anti-oxidant supports helps me stay focused.
I was so excited to try this but it hasn’t helped my back pain whatsoever. I’ve been taking it for 2 months and I’m going to give it one more month. I am taking the 500 and have doubled the dose making it 1000 mg. So disappointed.I thought in the beginning that it was giving me a little more energy. Maybe it has. I love the company. It is so easy to order and it’s shipped right away.
Fourth, CBD oil is believed to be effective against pain and inflammation, and, in its pure form, it's generally regarded as safe. Especially in light of the theory that ME/CFS is related to neuroinflammation, and the wealth of evidence pointing to it being an inflammatory disease, it's pretty obvious that there's a potential benefit that should be explored.

If you live in a state where CBD is legal for your condition, it’s best to buy it from a state-regulated dispensary. But even there, oversight is uneven. “I feel safe being a cannabis consumer in Colorado, since the state tracks everything from seed to sale, but I didn’t the first few years after cannabis became legal,” when the rules were still taking shape, says Robyn Griggs Lawrence, the Boulder author of The Cannabis Kitchen Cookbook, which features recipes for cannabis edibles.

Cannabidiol can be taken into the body in multiple different ways, including by inhalation of cannabis smoke or vapor, as an aerosol spray into the cheek, and by mouth. It may be supplied as CBD oil containing only CBD as the active ingredient (no added THC or terpenes), a full-plant CBD-dominant hemp extract oil, capsules, dried cannabis, or as a prescription liquid solution.[2] CBD does not have the same psychoactivity as THC,[8][9][10] and may affect the actions of THC.[6][7][8][11] Although in vitro studies indicate CBD may interact with different biological targets, including cannabinoid receptors and other neurotransmitter receptors,[8][12] the mechanism of action for its possible biological effects has not been determined, as of 2018.[7][8]
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