The reason so many people are interested in cannabis products that don’t make them high, proponents say, is that CBD helps with everything from pain and nausea to rheumatoid arthritis, cancer, Crohn’s disease, and dementia. CBD is anti-inflammatory, anti-anxiety, antibacterial, immunosuppressive, and more, says Joseph Cohen, D.O., a cannabis doctor in Boulder, CO.
Condensed CBD oil can be taken as a thick paste, but this is the least pleasant option. More commonly, the CBD oil is mixed with a carrier oil, such as hemp oil or coconut oil, to a specific concentration of CBD. The distinctive taste — which comes from the terpenes and not the cannabinoids — is often masked with chocolate, mint, or other flavorings. It typically comes in a small bottle with a dropper to administer the oil mixture.
I suffer fr migraines. Currently having Botox injections every three months for the last three years. This has helped went fr 24 to 30 migraines a month to 6 to 8 , now I'm back up to 14 to 20 a month. My doctor thought CBD oil might help. I have also started having anxiety attacks for a year now. I'm really confused with the dosages. Any thoughts would b helpful
Hemp Oil is processed from the seeds and stalks of the hemp plant and despite its source, it contains little to none of the psychoactive element Tetrahydrocannabinol (THC), meaning it cannot get you ‘high’. For instance hemp may contain 0.3-1.5% of THC whilst marijuana contains anything from 5% to 20% plus. Hemp oils main components are in fact omega fatty acids, similar to those which can be found in fish and olive oil.
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Under federal law, cannabis (from which both CBD and marijuana are derived) is illegal everywhere, although the laws against it aren’t generally enforced in states that have legalized marijuana. Some manufacturers claim that CBD culled from legally imported industrial hemp, which has little to no THC, is fine to ship across the U.S., but many experts disagree, noting that because hemp comes from the same species as marijuana, cannabis sativa, all CBD falls under the DEA’s Schedule 1 designation. “This creative interpretation of the law runs afoul of reality,” says the Brookings Institution, a Washington, DC, think tank.
Can cannabis help treat psoriasis? The active cannabinoids in cannabis may be an effective treatment for psoriasis. Research shows that they offer potential health benefits that could relieve the symptoms of psoriasis. They may be able to reduce inflammation and itching, control pain, and even heal wounds. Learn more about cannabis for psoriasis here. Read now
Ive been taking CBD tincture oil for 8 months now. It has made such a positive improvement in my life. I have more energy and I feel better overall. I feel like myself after many years of an overall feeling of lethargy. After taking CBD oil for 6 months, I went to my doctor for a regular check up. All my my bloodwork test results- including A1C and cholesteral- improved. As an added bonus, I lost 25 lbs. All of this without even trying. Adding CBD to my life has given me more energy. I feel like my metabolism has improved. Nowadays, I look forward to each day as what can I do today, while before CBD, my attitude was negative and what do I have to do today. Nothing else in my life has changed. In fact, it has become more stressful due to family illness. But CBD has taken the edge off and continues to be my go-to daily supplement. I use Medterra 500mg tincture oil and take 1/2 a dropper twice a day. Everyone is different, so adjust the amount and strength until you find what works best for you. Definitely do it. Take CBD. Youll be so happy that you did.
Do you think CBD oil may be right for you? Then check out Green Roads CBD oils for the highest-quality CBD tinctures on the market! We offer CBD hemp oil tinctures in a different range of dosages, from 100mg to 3500mg per bottle, to meet your specific needs. Designed to fit into your daily routine and easy to buy online, Green Roads CBD oils were made with our customers in mind.
A. The agency has received reports of adverse events in patients using marijuana to treat medical conditions. The FDA is currently reviewing those reports and will continue to monitor adverse event reports for any safety signals attributable to marijuana and marijuana products, with a focus on serious adverse effects associated with the use of marijuana.
Management of chronic pain is another application for which CBD is ideally suited, and it works in a number of ways. It and other non-THC cannabinoids found in hemp flower-bud extracts work to block pain-conducting nerve impulses, which reduces your perception of pain. Stimulation of CB1 in the brain increases dopamine, which counteracts pain. Just as importantly, these same chemical substances reduce inflammation, the driving force behind pain, which allows healing to occur.
Quality is a particular concern, because cannabis plants easily soak up heavy metals from pesticides and other contaminants, Marcu says. If you are buying online, look for a company that documents how it tests its products. (If the website doesn’t indicate this, call and ask.) “Buying from a reputable manufacturer is crucial, because it matters how the plant is cultivated and processed,” Dr. Maroon says. One clue that a company is cutting corners: too low a cost. Good CBD is pricey—a bottle of high-quality capsules is sold in Cohen’s office for $140. But for many, it’s worth the money. Roth spent $60 on her tiny bottle. But when her energy returned the day she started taking CBD, she decided that was a small price to pay.
Hemp Bombs is based in Tampa, Florida, and in addition to focusing on the purity and therapeutic effectiveness of their products, are dedicated to establishing themselves as a top brand in the industry with a specific target audience. One of our personal favorite products of theirs is the flavored CBD vape liquids, which are some of the best-tasting CBD vape juices we’ve ever had.

REM behavior disorder: REM behavior disorder (RBD) is a parasomnia disorder characterized by shouting, becoming physically agitated, or otherwise acting out during sleep. For many, RBD is a symptom of a larger, more serious condition or disorder, such as Alzheimer’s disease or PTSD. CBD oil minimizes the symptoms of RBD, and also alleviates the anxiety and painful symptoms that often accompany disorders that lead to RBD.
CBD can be very pricey, and much of it is sold through multi-level marketing schemes, which I don’t like. Dosing isn’t precise (or well-explained); it would be very helpful to have informed guidance in this area. As it is, I break down any product I buy to cost-per-mg, and cost-per-serving, which helps, but I’m still not sure how much is too much or too little. I tell my husband to “listen to [his] body,” but that can be risky.
My husband has RSD and we are considering CBD oil -= I would ask at Hempmed because the spray won't have enough in it. Our dgt';s friend has ovarian cancer and it is shrinking her tumors but the spray would never have been enough. I would get CBD oil and check with Hempmeds to see what they suggest. It isn't cheap but it does work. LOW dose Naltrexone about 4.5 mg is very helpful for RSD and is usually used for getting people off of drugs but is working on turning off the glial cells that surround the nerve that is causing the nerve to scream in pain. We are also using PeaPure that is out of the Netherlands and we are seeing a response, even though small. His other leg touched the painful leg without causing more severe pain. That is progress. We also are using Poison Ivy Cream through Meadowlake Farms that has helped the burning surface pain. Change your diet and get rid of Gluten and Sugar, anything that causes inflammation. This is to allow your own body to work. Absolutely do not use any pain killers as it will turn up your pain. all the Hydrocodone, etc causes neural inflammation and so it will keep cascading higher your pain. Hope this is helpful. Mary

Everyone needs a lip balm in a tube for on-the-go situations, and Colorado-based Ambary Gardens made a clear version with a faint lemon scent and only seven ingredients including CBD extract. It doesn’t leave your lips glossy or shiny or sticky—it just adds a layer of hydrated protection on the surface of your lips. While I’ve yet to try this on chapped lips, I imagine it’s a quick fix for quick relief, no glossy residue left behind.
A 2008 study found, “that a controlled cannabis extract, containing multiple cannabinoids, in a defined ratio, and other non-cannabinoid fractions (terpenes and flavonoids) provided better antinociceptive efficacy than the single cannabinoid given alone…” This is why the use of full-spectrum CBD oil is more effective in treating pain than taking CBD isolate alone – you want the beneficial terpenes and flavonoids contained in the plant.
Of course, because legal marijuana is in such a confusing transitional period, even here there are potential exceptions. The U.S. Food and Drug Administration (FDA) approved Epidiolex, a treatment for a rare form of pediatric epilepsy that contains CBD. The DEA decided to classify this as a Schedule 5 drug, the scheduling that indicates the lowest potential for addiction and abuse.

A non-intoxicating cannabinoid found in cannabis. After tetrahydrocannabinol (THC), cannabidiol (CBD) is the second-most abundant cannabinoid in the plant, and has many potential therapeutic benefits, including anti-inflammatory, analgesic, anti-anxiety and seizure-suppressant properties. Cannabidiol can be sourced from both marijuana plants and hemp plants, which are legal in most countries as they contain minor amounts of THC.  
The oil contained in the hemp seed is 75-80% polyunsaturated fatty acids (the good fats) and only 9-11% of the less desired saturated fatty acids. Hemp seed oil is reputed to be the most unsaturated oil derived from the plant kingdom. The essential fatty acids contained in hemp seed oil are required in our diet more than any other vitamin, yet our bodies do not naturally produce them. They must be obtained from external sources in the food we eat. Essential fatty acids are involved with producing life's energy throughout the human body and without them, life is not possible. In general, North Americans have a high dietary deficiency in essential fatty acids due to our high intake of animal fats versus plant fats, caused by our high consumption of processed foods and meats versus natural organic foods.
fibromyalgia, crps/rsd,carpel tunnel in both wrists, tendonitis, chronic migraine. mj has been effective in controlling my pain, spasms, tension and ive even had a slight improvement of my depression BECAUSE much of my depression is because of the medications i was taking AND the new limitations, changes in capabilities and problems that my body has brought on.All these thanks to Dr Mark Donald for providing me with CBD/low THC Cannabis Oil ratio 2 : 1(10): 3-4 puffs per day .Get to him via his number 313- 923-7690 .
Buying CBD OIL has never been easier.  Since CBD Oil from the Hemp plant does not contain unlawful measures of THC, it is legitimate in every one of the 50 states. This is imperative to individuals everywhere throughout the US who need CBD however can’t get it locally. What’s more, legitimate CBD is accessible for home conveyance in every one of the 50 states meaning numerous individuals don’t need to move to a state with sanctioned Medical Marijuana. Additionally, in states where medicinal weed is lawful, buyers utilizing this hemp plant type of CBD don’t need to obtain a medical marijuana card.

Sleep is an extremely important aspect of life. It is the time our bodies and brains rejuvenate ourselves and prepare us for the next day. Without good quality sleep, the toll on our bodies and mental capacities really adds up. But CBD helps with sleep. On average, our patients’ sleep duration grew from 4 ½ to 6 hours, and they reported that the quality of sleep was significantly improved. Patients even told us that they started remembering dreams, which was a surprise for them. Given the amount of medications these patients take, it’s no wonder many of them had not dreamed in years.
While CBD can be extracted from non-hemp varieties of the plant, hemp-derived CBD is less restricted by the government because of its inherently low levels of THC. CBD from hemp is legal for sale in most US states, while CBD products derived from non-hemp varieties can contain noticeable amounts of THC, and are therefore subject to stricter laws and regulations.
One of the first bioprospecting groups that attempted to implement the goals and guidelines of the CBD was a collaboration between the pharmaceutical firm Merck & Company and Costa Rica's Instituto Nacional de Biodiversidad (INBio), a private, nonprofit conservation and research group, INBio agreed to provide Merck with a limited number of plants, fungi, and other samples from Costa Rica's protected areas for scientific and commercial evaluation.
The most commonly used form of CBD is CBD oil. Combining CBD extract with a carrier oil like coconut oil, it can be ingested or vaped, bringing a lot of variety. But because marijuana legalization is in such a murky situation with both federal and state laws to grapple with, CBD oil's legality can be hard to parse depending on where you are. Let's start with legality at the federal level.

Cannabidiol (CBD) has NOT been proven to treat, relieve, nor cure any disease or medical condition listed on this site. The medical studies, controlled tests, and health information offered on Cannabidiol Life of allcbdoilbenefits.com (or any variation of the URL) is an expressed summarization of our personal conducted research done by me and few friends in the business. The information provided on this site is designed to support, NEVER replace, the relationship that exists between a patient/site visitor and the patient’s/site visitor’s physician.

In a SAFEX study of Phase III double-blind RCT in 160 subjects with various symptoms of MS (Wade et al 2004), 137 patients elected to continue on Sativex after the initial study (Wade et al 2006). Rapid declines were noted in the first twelve weeks in pain VAS (N = 47) with slower sustained improvements for more than one year. During that time, there was no escalation of dose indicating an absence of tolerance to the preparation. Similarly, no withdrawal effects were noted in a subset of patients who voluntarily stopped the medicine abruptly. Upon resumption, benefits resumed at the prior established dosages.


Cannabidiol is POSSIBLY SAFE when taken by mouth or sprayed under the tongue appropriately. Cannabidiol in doses of up to 300 mg daily have been taken by mouth safely for up to 6 months. Higher doses of 1200-1500 mg daily have been taken by mouth safely for up to 4 weeks. A prescription cannabidiol product (Epidiolex) is approved to be taken by mouth in doses of up to 10-20 mg/kg daily. Cannabidiol sprays that are applied under the tongue have been used in doses of 2.5 mg for up to 2 weeks.
Individuals with sleep disorders are likely to experience more intense pain as the body is unable to complete its natural healing process to alleviate some of the effects caused by arthritis, fibromyalgia, muscle injury, or other type of chronic pain. The danger with chronic pain is that it keeps the nerves engaged in a fight-or-flight state, which makes it extremely difficult to relax and fall asleep. CBD has neuroprotective properties that encourage rest and improve sleep.
CBD concentrates typically contain the strongest dosage of CBD compared to any other CBD products. It can contain up to 10 times the average CBD products. Concentrates are also convenient in that it only takes a few seconds to consume. Overall, CBD concentrates seem to be most popular among customers who are extremely busy, yet seek high potency CBD.
A major problem with cannabis is its short half life. It only lasts two hours. Repeated dosing of a chemical – that is what it is, natural or not, that makes you high is just not realistic if you want a life. It also has a horrid withdrawal syndrome if you are a regular user and then travel and can’t use for legal reasons. I almost ended up in Hospital it was VILE. And there are drug interactions. It makes me itch. What exactly it is reacting with from what I, prescribed I’m now sure. No since having an epidural it affects me like speed in a horrid way. I haven’t slept since 0230 and it’s now 2040, two night in the last week I didn’t sleep at all and I’ve been horribly manic.

CBD is a safe, long-term aid which is why it has gained such momentum and why our customers are turning to it for relief. CBD, scientifically known as cannabidiol, is a non-psychoactive, natural compound found in the hemp plant. When it interacts with the body’s endocannabinoid system, CBD provides powerful health benefits without the side effects of conventional drugs. The CBD utilized in our tinctures is extracted from industrial hemp cultivated in the United States. To further ensure quality and purity, our industrial hemp goes through a supercritical CO2 extraction process to obtain the best possible CBD solution. This solution is then formulated by our board-certified pharmacists into finished products and sent out for third-party testing. Our CBD oil is made with high-quality CBD extracted from natural hemp that is abundant in naturally produced terpenes, oils, vitamins, omega fatty acids, and other components.
Right: The brain contains a huge a number of brain cells (neurons). Each neuron, represented here as a hexagon, is connected to many others. Left: The synapse is the site where two neurons communicate with each other. The “sender neuron” releases chemical signals called neurotransmitters, which stimulate receptors on the “receiver neuron.” There are many different receptor types in the brain, each one sensitive to different neurotransmitters.
People claim that cannabis oil can be used to treat a wide range of conditions, though evidence to back up these claims is often lacking. For example, according to Medical News Today, people use cannabis oil for conditions ranging from pain to acne; some even claim the oil can cure diseases like Alzheimer's and cancer. (But again, there is no clinical evidence to support these claims.) 
A study analysis in Journal of Pain Research confirms that topical use of certain cannabinoid topicals can reduce pain in animals with inflammation or neuropathic pain. And science has found topical creams with THC and CBD help relieve pain for conditions like multiple sclerosis. But for the vast majority of chronic pain—and most certainly for acute pain like post-workout—the scientific jury is 100 percent still out. "There's a little bit of data in support of CBD for pain relief, but to go from animal to human is a giant leap," Sexton says.
A 2012 study reported that, “systemic and intrathecal administration of cannabidiol (CBD), a major nonpsychoactive component of marijuana, and its modified derivatives significantly suppress chronic inflammatory and neuropathic pain without causing apparent analgesic tolerance…These cannabinoids may represent a novel class of therapeutic agents for the treatment of chronic pain and other diseases…”
The 3000 tincture has been very helpful for me with: chronic & acute wide spread pain, headaches, anxiety, sleep, nausea, & allergies....not a complete cure, but a tremendous help with all of these, & with absolutely no side effects (& I am extremely susceptible to any side effects from meds & some supplements)....very happy to have found this product.
CBD is famous for the promise it holds for treating treatment-resistant forms of childhood epilepsy. A number of clinical trials, testing the efficacy of CBD in human epilepsy patients, are currently underway. But there is also evidence, mainly from animal studies and in vitro experiments, that CBD may have neuroprotective, anti-inflammatory and analgesic (pain-relieving) properties, and potential therapeutic value in the treatment of motivational disorders like depression, anxiety, and addiction.

Using hempseed oil in diet has a beneficial effect on acne. Its omega – 3 fatty acid content aids the body in reducing inflammation of the skin. This reduces the redness of pimples and may also prevent future breakouts.  Preventing breakouts with topical solutions can be very tough, as many products, even many natural oils are comedogenic ( block pores ) and lead to breakouts.
CBD strains can be consumed just as you would THC strains. You can smoke or vaporize CBD-rich flower, eat a CBD-infused edible, swallow a CBD oil capsule, apply a CBD lotion, or use a CBD tincture sublingually. Hemp products also contain CBD, though it is a less efficient source and lacks the beneficial chemical diversity of cannabis-derived CBD products (more on that here).
^ Nadulski T, Pragst F, Weinberg G, Roser P, Schnelle M, Fronk EM, Stadelmann AM (December 2005). "Randomized, double-blind, placebo-controlled study about the effects of cannabidiol (CBD) on the pharmacokinetics of Delta9-tetrahydrocannabinol (THC) after oral application of THC verses standardized cannabis extract". Ther Drug Monit. 27 (6): 799–810. PMID 16306858.

In addition to the daily pain management program outlined above, many people find they still need a safe way to manage acute flare ups. Whether it’s caused by a recent injury, cold weather, or general aggravation  – we recommend vaporizing CBD isolate to combat these acute pain flare ups. The benefit of vaporizing or dabbing CBD isolate is that the relief can be felt almost instantaneously. CBD isolate is 99% pure CBD and provides a wave of relief that can be felt throughout the whole body.
This takes us to the next problem: There is no regulation around how much active CBD or THC is in each cream or how much of the compound is needed to see relief. Read: "If you have three products that say 1 percent CBD infused in coconut oil, one could be great and the other two could be crap—that's the reality of cannabis medicine right now," Gerdeman says.
According to PeaceHealth, a website dedicated to providing information on an array of different supplements and medications, hemp oil can cause minor side effects in the digestive system. For example, the website suggests that hemp and hemp oil can soften the stools, often leading to diarrhea or abdominal cramping. Many times, excessive diarrhea can lead to increased weight loss or malabsorption. While further research is needed to substantiate these side effect claims, it is recommended that for individuals with a history of digestive disorders or irregular bowel movements to not take hemp oil supplements.
“The brain has these receptors that respond to endocannabinoids, which are neurotransmitters that are naturally produced in the body and brain,” says Jerald Simmons, a neurologist at Houston’s Comprehensive Sleep Medicine Associates. “Some of the cannabinoids in the marijuana plant are very similar to the endocannabinoids in the brain, and they act on the same receptors.”
Cannabinoid agonists produce many effects beyond those mediated directly on receptors, including anti-inflammatory effects and interactions with various other neurotransmitter systems (previously reviewed (Russo 2006a). Briefly stated, THC effects in serotonergic systems are widespread, including its ability to decrease 5-hydroxytryptamine (5-HT) release from platelets (Volfe et al 1985), increase its cerebral production and decrease synaptosomal uptake (Spadone 1991). THC may affect many mechanisms of the trigeminovascular system in migraine (Akerman et al 2003; Akerman et al 2004; Akerman et al 2007; Russo 1998; Russo 2001). Dopaminergic blocking actions of THC (Müller-Vahl et al 1999) may also contribute to analgesic benefits.
Furthermore, oil has been found to be beneficial in the treatment of specific skin conditions including eczema, dermatitis, psoriasis, and acne rosacea. Favorable results likely relate to the  GLA component of hemp oil.  In addition to moisturizing, the oil is also used to relieve discomfort associated with itchy skin. Other benefits may include skin strengthening, which enhances the skin’s role in resisting viral, fungal, and bacterial infections.
For example, Charlotte's Web Holdings (NASDAQOTH:CWBHF), which is one of a very small handful of marijuana stocks to have generated an operating profit without the help of one-time benefits or fair-value adjustments, has its line of CBD products in more than 3,600 U.S retailers. The passage of the Farm Bill was expected to rapidly expand this retail presence, with Charlotte's Web leaning on CBD derived from hemp plants. However, demand for CBD products may prove less robust than initially thought as a result of regulatory pushback against CBD-infused edibles. This might have the potential to adversely affect Charlotte's Web's near-term growth prospects.
A clinical endocannabinoid deficiency has been postulated to be operative in certain treatment-resistant conditions (Russo 2004), and has received recent support in findings that anandamide levels are reduced over controls in migraineurs (Sarchielli et al 2006), that a subset of fibromyalgia patients reported significant decreased pain after THC treatment (Schley et al 2006), and the active role of the ECS in intestinal pain and motility in irritable bowel syndrome (Massa and Monory 2006) wherein anecdotal efficacy of cannabinoid treatments have also been claimed.
I just started taking CBD oil , I am on my 2nd Hip replacement surgery due to device failures looking at a 3rd surgery. Has you can imagine the pain, stress and anxiety levels are off the charts. Especially at an otherwise healthy 54 yr women. So i understand from reading posts its best to take it under the tongue. I am taking 1-2 ml a day. I can tell some difference,is your recommended dosage. I am using for pain , stress and sleep. I appreciate your feedback.

As noted in the previous section, CBD oil prices vary significantly by brand. The best practice for most is to determine a per-milligram budget for CBD oil, as well as a maximum price for the entire bottle. For example, you might decide that 10 cents per milligram or less is a reasonable budget; and that $45 (for a 450-mg concentration, based on the budget) is a maximum bottle price. Also, if ordering online, be sure to include potential shipping costs.


CBD has really helped me reduce my anxiety and difficulty to focus while studying. I used to fidget quite a bit when i was sitting for a long time although i never had learning disabilities of any sort. Now i have no problem sitting and reading for long times. This stuff has turned my brain into a Ferrarri engine in terms of learning, I’m going through new concepts really fast it’s pretty exciting. All this with less than 10 mg per day of CBD (a few drops sublingually throughout the day, from a concentrated product). If only it was easier to get good quality stuff.
Epilepsy. A specific cannabidiol product (Epidiolex, GW Pharmaceuticals) has been shown to reduce seizures in adults and children with various conditions that are linked with seizures. This product is a prescription drug for treating seizures caused by Dravet syndrome or Lennox-Gastaut syndrome. It has also been shown to reduce seizures in people with tuberous sclerosis complex, Sturge-Weber syndrome, and febrile infection-related epilepsy syndrome (FIRES). But it's not approved for treating these other types of seizures.
The problem here is that the FDA views this clinical indication as statistically significant for patients with Dravet syndrome and Lennox-Gastaut syndrome, and unconfirmed for every other possible ailment. Even with university-based data suggesting that CBD treatments can help with chronic pain or glaucoma, that's not been proven by an FDA-cleared study. And since the "F" in the FDA stands for "Food," adding an unproven substance to food items creates a big gray area for the time being.
The ECS is responsible for setting the baseline activity levels of our immune system and nervous system, which then work to maintain our health. When the ECS falls out of whack, the systems that are regulated by it can begin to malfunction. CBD promotes the normal health and function of the endocannabinoid system, so it’s possible that CBD can help to alleviate the symptoms of conditions that are caused by dysfunction of the endocannabinoid system.
Results of a Phase III study (N = 177) comparing Sativex, THC-predominant extract and placebo in intractable pain due to cancer unresponsive to opiates (Johnson and Potts 2005) demonstrated that Sativex produced highly statistically significant improvements in analgesia (Table 1), while the THC-predominant extract failed to produce statistical demarcation from placebo, suggesting the presence of CBD in the Sativex preparation was crucial to attain significant pain relief.

Ajulemic acid (CT3, IP-751) (Figure 1), another synthetic dimethylheptyl analogue, was employed in a Phase II RCT in 21 subjects with improvement in peripheral neuropathic pain (Karst et al 2003) (Table 1). Part of its analgesic activity may relate to binding to intracellular peroxisome proliferator-activator receptor gamma (Liu et al 2003). Peak plasma concentrations have generally been attained in 1–2 hours, but with delays up to 4–5 hours is some subjects (Karst et al 2003). Debate surrounds the degree of psychoactivity associated with the drug (Dyson et al 2005). Current research is confined to the indication of interstitial cystitis.
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