Industrial hemp contains, by weight, far less CBD than CBD-rich cultivars such as Harlequin or Sour Tsunami. This means that producing a single 10 mL dose of CBD would require the cultivation and extraction of far more hemp than it would from whole-plant marijuana; thus raising the risk of exposing users to more contaminants. Hemp is classified as a “bioaccumulator,” or a plant that naturally absorbs toxicants from the soil.
I have/had ovarian/primary peritoneal cancer. I used thc/cbd oil pills I self made from the start. I am supposedly their “poster child”. I went thru with chemo and surgery. Oh that horror! But when I tried to tell two seperate doctors, the surgeon was all about it, and my oncologist threw a fit and said it was an anecdote. There are more than 100 studies at the NIH govt website.
Areyo, I would like to ask you a couple of questions if I may please.If one used this CBD oil would it cause a drug test to appear as though one were using marijuana? I’m pretty sure I already know the answer but would like one confirmed please. Secondly what are the side effects of this particular remedy? Seems this day in age everything has a side effect. The difference in this remedy sounds remarkable compared to plain old marijuana and the side effects that accompanie it. Can you explain in detail just how this is possible? How much would it cost the average chronic pain patient per month? I’m going to assume this isn’t on the approved drug list for those with insurance. In the meantime if it does come with any ill side effects and will eventually be proven dangerous (there for being taken off the market if it is approved) what is the difference between this and opioids? For those of us that are fortunate enough to be left with a compassionate doctor who sees fit to prescribe those of us with chronic pain the limited opioid dosage, I truly don’t see how this could be added to the mix so to speak. Although if in time if our government continues with its dastardly plan, just how would one go about obtaining this remedy? Through mail- order, or through ones doctor? If our government continues to take all pain medication away primarily made of opioids then there has got to be some sort of an alternative left. Something other than Tylenol, aspirins and goody powders. For myself, other than aspirin all other NSAIDs are off the table for they make me incredibly sick. Tylenol and goody powders also come with great risks after years of use. At least with a doctor prescribing our opioids we were all kept from taking too much Tylenol, aspirin and too many goody powders. I for one know that with being prescribed opioids I never even considered having to mix in marijuana, alcohol or consider suicide as an alternative. Thank you for your story, time and consideration.

Reality: Hemp oil is an increasingly popular product, used for an expanding variety of purposes. The washed hemp seed contains no THC at all. The tiny amounts of THC contained in industrial hemp are in the glands of the plant itself. Sometimes, in the manufacturing process, some THC- and CBD-containing resin sticks to the seed, resulting in traces of THC in the oil that is produced. The concentration of these cannabinoids in the oil is infinitesimal. No one can get high from using hemp oil.

Perhaps the biggest concern for anybody with a job or kids or other responsibilities is whether CBD will induce psychoactive effects. While it’s true that CBD comes from cannabis plants, it does not cause any high. The two main compounds in cannabis are CBD and THC; and they are completely different in the effects they generate in the body. THC makes you high, but CBD stabilizes cognitive and neurological functions.
Cannabidiol, better known as CBD, is having a major moment. Most commonly consumed as an oil, the marijuana compound doesn't give you that floaty feeling of being high—but it does have its own set of uplifting properties. CBD oil users say it melts away anxiety, eases sleep issues, and relieves depression. And last month, the U.S. Food and Drug Administration approved CBD to treat two severe forms of epilepsy, making it the first marijuana-derived drug approved at the federal level.

Hemp oil can come from the flower, leaves, stock or seeds. If it comes from the seed there are no cannabinoids found. If it comes from the rest of the plant cannabinoids are found. Hemp extract usually refers to either CBD or oil from the stock, flower, or leaves. Our Virgin cannabis sativa hemp oil is a hemp seed oil, and our Premium hemp oil products, have hemp oil from the stem of the plant (which is listed in milligrams on the bottle) It also has hemp seed oil in the bottle to act as a carrier oil. Our Hemp seed oil is a cold pressed seed oil, and our Premium hemp oil that comes from the stem is Co2 extracted.
Great public concern attends recreational cannabis usage and risks of dependency. The addictive potential of a drug is assessed on the basis of five elements: intoxication, reinforcement, tolerance, withdrawal and dependency. Drug abuse liability (DAL) is also assessed by examining a drug's rates of abuse and diversion. US Congress placed cannabis in Schedule I of the Controlled Substances Act in 1970, with drugs categorized as addictive, dangerous, possessing severe abuse potential and no recognized medical value. Marinol was placed in Schedule II, the category for drugs with high abuse potential and liability to produce dependency, but certain recognized medical uses, after its FDA approval in 1985. Marinol was reassigned to Schedule III in 1999, a category denoting a lesser potential for abuse or lower dependency risk after documentation that little abuse or diversion (Calhoun et al 1998) had occurred. Nabilone was placed and has remained in Schedule II since 1985.
Unfortunately, due to strict FDA laws, I am not legally able to say that CBD will help with your husbands specific condition, however I can direct you to some literature to help you better understand what CBD may offer. I have attached links below. As far as strength and dosage goes, tinctures and concentrates are absorbed the fastest since it goes directly into your blood stream; the dosage on these can be measured and controlled. Capsules take a little longer to enter your body since it goes through your digestive tract, these are also measured and controlled. I would recommend reading through our page on dosing as well to get a better understanding.https://cbdoilreview.org/cbd-cannabidiol/https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage/I hope these help :)

The nervous system’s endocannabinoid system is not well understood. But it’s thought to play a role in regulating pain, sleep, mood, memory, appetite, and other cognitive and physical processes. Because CBD is able to mimic the actions of some natural brain chemicals, its potential therapeutic benefits are wide-ranging but—at this point—nebulous. “We know that cannabidiol modulates the endocannabinoid system, but we don’t know how it works,” Szaflarski says. That said, there are theories.
Until 2017, products containing cannabidiol marketed for medical purposes were classed as medicines by the UK regulatory body, the Medicines and Healthcare products Regulatory Agency (MHRA) and could not be marketed without regulatory approval for the medical claims.[89] As of 2018, cannabis oil is legal to possess, buy, and sell in the UK, providing the product does not contain more than 0.2% THC and is not advertised as providing a medicinal benefit.[90]
In this edition of Cannabis Conversations, Project CBD Director, Martin A. Lee, discusses the benefits of CBD, the "entourage effect" and the microbiome with Dr. Ethan Russo. A neurologist, scientist, and widely published author, Dr. Russo is currently the director of research and development at the International Cannabis and Cannabinoids Institute in Prague (www.icci.science).
Based on reviews, smoking or vaporizing CBD vape oil seems to have less effects when compared to other methods of administering CBD, such as tinctures, capsules and sprays. On the flip side, others argue that smoking or vaporizing has less drawbacks than taking CBD orally, since ingesting CBD orally could result in inconsistent absorption and a delayed effect.
Because CBD oil products are mostly unregulated, there’s no guarantee that any given product contains a safe or effective level of CBD. In fact, a study published in the Journal of the American Medical Association in 2017 found that nearly 70 percent of all CBD products sold online are incorrectly labeled, and could cause serious harm to consumers. Some CBD oils may also contain incorrectly labeled amounts of THC and other compounds.
For those who, you may have seen that the opioid crisis is becoming an epidemic in the country. There are millions of people who are addicted to some form of opioid and who will do just about anything to get their hands on it. What isn’t talked about often is the fact that most of these people became addicted to this drug through prescription medicine they are given to combat the pain they are feeling. The assistance doctors are prescribing actually became the source of their addiction.
To calculate the cost per milligram of CBD, simply divide the dollar amount of the product by the total milligrams of CBD in the bottle. So for instance, a product with 600 mg CBD in a 1 fluid-ounce bottle costing $80 is equal to about 13 cents per mg of CBD; a product with 100 mg of CBD in the same size bottle selling for $40 works out to 40 cents per mg of CBD. In this case, it pays to splurge on the $80 bottle.
Outside of the aforementioned studies, CBD’s progress toward its place in society today suffered from intermittent spurts and starts until 1996 when California became the first US state to legalize medical cannabis. This groundbreaking moment paved the way for public support and lucrative research opportunities. Other states including Oregon, Alaska, Washington, Maine, Hawaii, Nevada, and Colorado would follow suit before the close of 2000.
While research into the effects of CBD on specific conditions is important, a broader perspective on the relationship between CBD and the human body is necessary to understand how this unique compound works. Interestingly, many of the conditions that are supposedly helped by CBD have no well-understood cause, from acne to Alzheimer’s disease. However, one of the few common denominators between these conditions is the involvement of the endocannabinoid system (ECS) in their causes.

To start I read many reviews, because I was curious. I've lived with chronic pain for years and haven't had a prescription yet that helped or even partially touched the pain. I was reading about Hemp oil, CBD oil etc. on YouTube and that got me started checking this item out. The CBD oil is so expensive I couldn't buy it because that's a lot of money for something that might not work. I checked Amazon and they had it cheaper, but still expensive enough I didn't want to take the chance.

These statements have not been evaluated by the Food and Drug Administration (FDA). These products are not meant to diagnose, treat or cure any disease or medical condition. Please consult your doctor before starting any exercise or nutritional supplement program or before using these or any product during pregnancy or if you have a serious medical condition.
Because of this classification, it's not easy for researchers to get their hands on the drug. "That's not to say you can't do it, but there are hoops you need to jump through that can be a pain, which may deter researchers from going into this space," Bonn-Miller said. "Relatively speaking, it's a small group of people in the U.S. that do research on cannabinoids in humans."
Cannabis has been around for thousands of years and is believed to have originated in South or Central Asia. The two main species of cannabis are Cannabis sativa and Cannabis indica. Both Cannabis sativa and indica contain varying amounts of psychoactive and nonpsychoactive components. Cannabis sativa is more commonly known for its stimulatory, mental effects while Cannabis indica is more known for its relaxing, body-calming effects.

In medical use for pain relief, doctors prefer the CBD varieties of cannabis extract over THC, primarily due to their lack of side effects. Supplements combining CBD and THC, such as Sativix, have shown the best results in adults in clinical trials. Although experts prefer CBD because it has no side-effects, combining both CBD and THC might be the most effective way to treat pain.
CBD Isolate is the purest supplement available. It’s a 99% pure CBD supplement derived from hemp oil. Despite its concentration, CBD isolate effects are similar to other CBD concentrates, and it can be used in a variety of ways. It can be consumed itself, added to foods and beverages, or vaporized. You can also add it to other CBD products to increase their potency.
Hemp Seed Oil is derived from the hemp seeds and are mainly used for dietary purposes (imagine something similar to coconut oil). Refined hemp seed oil can also be used in beauty care products, as they have amazing skin care properties. CBD Hemp oil is not the same thing as hemp seed oil, as it is extracted from one of hemp’s many cannabinoids and have fundamentally different properties.
Just wanted to share with you that I have been ordering oil for my sister-in-law who had a Glioblastoma Multiform Brain Tumour. After surgery, 6 weeks of radiotherapy and 3 months of chemo (plus your amazing M10P treatments), my sister-in-law is tumour free as of today! Thank you so much for the service you provide. Feel free to share this story with other members who need a boost and some good news! Thanks again
There are a few other drawbacks to studies on CBD. First off, many involve rats rather than humans (including one that focuses on arthritis-related ache relief). Also, the science that does involve people doesn’t often include a large test group, Craft says. Finally, as Craft notes along with a review of CBD studies, there’s not much research out there about the long-term effects of cannabis-based meds.
I rely heavily on chiropractic care and medications. And, yet, the one, almost laughable thing I didn’t know about was hemp oil. When my friend told me she was a representative for a hemp oil company, and thought it would be helpful for my peripheral neuropathy at night, I just stood there with my mouth open. I had no idea about what it was or how it differed from medical marijuana, even.
Mary had been battling horrible arthritis pain for years, which she was barely able to control. Enduring this mind-numbing pain was bad enough but what happened next was nothing short of a nightmare. Without warning... Mary suffered two major strokes in 67 days! Miraculously, Mary survived but her arthritis raged hopelessly out of control as a result of the strokes.
The degree to which cannabinoid analgesics will be adopted into adjunctive pain management practices currently remains to be determined. Data on Sativex use in Canada for the last reported 6-month period (January-July 2007) indicated that 81% of prescriptions issued for patients in that interval were refills (data on file, from Brogan Inc Rx Dynamics), thus indicating in some degree an acceptance of, and a desire to, continue such treatment. Given their multi-modality effects upon various nociceptive pathways, their adjunctive side benefits, the efficacy and safety profiles to date of specific preparations in advanced clinical trials, and the complementary mechanisms and advantages of their combination with opioid therapy, the future for cannabinoid therapeutics appears very bright, indeed.
I suffer from severe anxiety characterized by random panic attacks depression. Medication has not been helping. We moved and I stopped doing all the things I use to enjoy. Within days of using this product I was back doing the things I love. I cannot believe the amount of relief I get from this miraculous product. Zero unpleasant taste easy to take I have no complaints other than I wish I wouldve found this product years ago. Ive recommended it to everyone I know and I dont plan on ever being without it from now on. Looking forward to completely weening off my medication because I believe this product will help me more with no side affects. Do yourself a favor and start taking this there is a solution and this is it

In the United States, we saw the U.S. Food and Drug Administration (FDA) approve its very first cannabis-derived drug in June, saw a handful of new states give the green light to pot during midterm elections, and observed as President Trump legalized hemp and hemp-based cannabidiol (CBD) in December by signing the Farm Bill into law. CBD is the nonpsychoactive cannabinoid best known for its medical benefits. 
Ringo’s Gift: This cultivar is named after the cannabidiol pioneer, Lawrence Ringo. Ringo’s Gift is a cross between two other CBD-rich strains, AC/DC and Harle-tsu. Its CBD to THC ratio varies from 1:1 to 22:1, but it consistently favors CBD. Ringo’s Gift smells of earthy pine and promises full-bodied relaxation in tandem with calming cerebral effects which, together, silence pain and anxiety.
In 2015, The Hebrew University of Israel published a study that documented the potency of single-molecule CBD extract versus the potency of whole-plant CBD-rich extract. It found that extract taken from whole plant CBD-rich cannabis is therapeutically superior to single-molecule extract. The scientists behind this study noticed that science had been utilizing pure, single-molecule CBD, which resulted in a bell-shaped dose-response curve. This means that CBD’s efficacy plummets at very high and very low doses.
I was diagnosed with vasovagal syncope and in April began have seisures and black outs multiple times a day. I began taking CBD oil on September 1st. Within a week or so I stopped blacking out as often and came to faster. By the end of September Id switched to your product because of the purity. A HUGE IMPROVEMENT Ive been using your 1000 mg bottle for 6 weeks now. Im taking less in the morning and evening. I no longer need a mid day dose. As the weeks go by Ive had no black outs no seisures in several weeks. My energy level has improved my chest pains have gone away. My panic attacks have gone to next to nothing. Ive been able to clean and go out again. Thank you for giving me my quality of life back again. It surely beats taking prescription drugs and dealing with side effects. Only side effects Ive noticed was I stopped sweating profusely everyday and my appetite has decreased and Ive lost a few pounds. YEAH

Imagine not being able to sleep and becoming chronically sleep deprived. Imagine not being able to find a comfortable position to sit, stand or sleep. Imagine your significant other or children wanting your attention and you not having the capacity to give any. Imagine not being able to have enjoyable sex with the one you love. Experiencing chronic pain continuously changes you. It will make you crazy. Depression and anxiety are commonplace among this patient population.
Due to the circumstances out of our control, the Black Friday sale will start as soon as our payment processor comes back online. Rest assured that once the payment processor is up and running again, we will be running the best Black Friday sale ever and we will allow plenty of time for orders to be placed! We are working around the clock to resolve this.
Cannatonic: A potent pain-reliever, Cannatonic hails from Spain and stands as one of the earliest cultivars to be bred for its high CBD content. This cultivar is a cross between MK Ultra and G13 Haze, and it helps relieves anxiety, muscle spasms, pain, and migraines while providing uplifting energy. Cannatonic tends to relax and loosen muscles without locking users to their couches.

To start I read many reviews, because I was curious. I've lived with chronic pain for years and haven't had a prescription yet that helped or even partially touched the pain. I was reading about Hemp oil, CBD oil etc. on YouTube and that got me started checking this item out. The CBD oil is so expensive I couldn't buy it because that's a lot of money for something that might not work. I checked Amazon and they had it cheaper, but still expensive enough I didn't want to take the chance.
Inhibited liver function: The liver regulates the way different drugs are metabolized within the body; this process is known as hepatic drug metabolism. Higher-than-average doses of CBD oil can slow the hepatic drug metabolism process. As a result, users may not be able to process other drugs as quickly. This is particularly concerning for CBD oil users who also take prescription medications.

One of the earliest success stories involves a young girl named Charlotte who was given an ingestible oil derived from Charlotte’s Web, a CBD strain that was specifically developed to provide her with all the benefits of the drug without the high. In less than two years, Charlotte went from a monthly seizure count of 1,200 to about three. Other success stories followed and more parents have begun to speak out, particularly parents who are desperate for access to this life-saving treatment.


Hi Diane, how did you go on with the CBD oil please. If it worked how long before you saw any results. I'm scared of flaring everything. Nerve damage across buttocks from a surgeon who found the nerve stuck to the bulge during a laminectomy operation and prised it off. I haven't sat for 5 years and getting worse. A muscle in my buttock is now throbbing constantly and causing pain to the muscle above. I've only started taking it today but the muscle pain is still as painful. Does it take a while for it to work. Only started on low dose to see what happens. Thank you Lyn

According to PeaceHealth, a website dedicated to providing information on an array of different supplements and medications, hemp oil can cause minor side effects in the digestive system. For example, the website suggests that hemp and hemp oil can soften the stools, often leading to diarrhea or abdominal cramping. Many times, excessive diarrhea can lead to increased weight loss or malabsorption. While further research is needed to substantiate these side effect claims, it is recommended that for individuals with a history of digestive disorders or irregular bowel movements to not take hemp oil supplements.
Even though most manufacturers claim that CBD does not have any side effects, research says otherwise. Sure, most people can tolerate the impact of CBD just fine, but a small portion of the population have been noted to experience not-so-adverse side effects. According to Cannabis and Cannabinoid Research, the most common results are tiredness, change in weight, diarrhea, fatigue.

Creams and salves for musculoskeletal discomfort generally contain very small amounts of CBD that are absorbed through the skin. Many of these products do provide significant benefit, however, but the benefit is likely derived from other aspects of CBD — especially terpenes from cannabis and essential oils, thanks to their anti-inflammatory properties.
Hi Marilyn, I would recommend a topical lotion or salve to start for instant relief.. Maybe 250 to 300 mg tincture to see how you feel. For me, the salve took the pain in my hands away in under a minute. I didn't notice how much the tincture worked until I forgot to take on vacation. Pain that was pretty much gone but came back, I was tired, grumpy and felt horrible. It works, just need to find right product and dosage for you.
Anecdotal evidence from patients is becoming increasingly widespread as well. Morgan Freeman suffers from pain and he was quoted saying, “I have fibromyalgia pain in my arm and the only thing that offers any relief is marijuana.” Whoopi Goldberg also uses cannabis to treat her daily pain from glaucoma and has even launched a line of medical cannabis products geared towards women suffering from menstrual pain.
Clinical trials allow us to draw conclusions about the safety and effectiveness of potential therapeutic agents in humans, while animal studies and in vitro experiments allow researchers to explore their biological actions in greater detail. However, because the latter class of studies are not conducted in humans, the results don’t always lead to the clinical application that we hope for—the majority of drugs that start in human clinical trials never become approved. Nonetheless, animal studies provide us with a strong foundation of biological knowledge, and are where the initial breakthroughs in research are made.
Ingredients: Water (Aqua), Carthamus Tinctorius (Safflower) Seed Oil, Cocos Nucifera (Coconut) Oil, Caprylic/Capric Triglyceride, Glycerin, Stearic Acid, Cetyl Alcohol, Glyceryl Stearate, PEG-100 Stearate, Argania Spinosa (Argan) Kernel Oil, Cannabis Sativa (Hemp) Seed Oil, Aloe Barbadensis Leaf Juice, Chamomilla Recutita Flower Extract, Symphytum Officinale Rhizome/Root Extract, Avena Sativa Extract, Citrus Aurantium Amara Flower Extract, Panax Ginseng Root Extract, Citrus Aurantium Dulcis Peel Extract, Ulmus Fulva Bark Extract, Oenothera Biennis Extract, Hemp Extract, Carbomer, Sodium Hydroxide, Ethylhexylglycerin, Phenoxyethanol, Fragrance (Parfum), Linalool, Eugenol, Limonene
This peach-hued sea salt soak is the perfect Sunday afternoon bath ritual—and unlike a trendy bath bomb, it won’t turn your tub water a different color. With ingredients like magnesium flakes (stronger than Epsom salts), pink Himalayan salt, arnica, and of course, CBD extract, these crystals provide proactive therapeutic relief while also relaxing your senses with lavender and clary sage essential oils. You can also use them to soak your feet after a long run, just as you would with Epsom salts.
Hello. I have stage 4 thyroid, secondary lymphoma..And many other health issues.I use 50mg of cbd vapor oil. 5 drops with each use. Total equals 250mg, about hits per dose, three times a day. I'm also on subsys, which is fentanyl. Idk about anyone but myself, but it's helped me with pain, with sleep, and in general my moods. So I dint have anything negative to say. I just hope that with time, proper diet, low dose chemo, and some other herbal usage, that I can shirk some of the cancer eating at my body... Thanks and good luck to you all.
Oral consumption of hemp oil may lead to the development of digestive problems due to its high-fat content. To avoid this side effect, only small amounts should be consumed at first. Research has also shown that the oil can interact with blood thinners. Thus, it is important to seek medical advice before consuming hemp oil to ensure that there are no contraindications or possible drug interaction risks.

They may be safe, but there's one massive problem: There's practically no scientific data to support the idea that a CBD-infused topical cream is any more effective than other topical pain relievers, like Tiger Balm, BenGay, or Icy Hot. Michelle Sexton, a San Diego-based naturopathic doctor and medical research director of the Center for the Study of Cannabis and Social Policy says that her patients do seem to have a great interest in CBD ointments, and roughly 40 percent of them have indeed tried one. However, these people are in her office now because the topicals didn’t work for them. "As a medical professional, my opinion is there’s little evidence to back up the claims being made—it’s all marketing for now," she says.


Depression is a common effect of chronic pain. When a person finds it impossible walk or go to work in the morning, it can have devastating effects on normal life. In addition to easing pain, CBD also triggers the release of serotonin and other “happy” chemicals in the body and numbs down brain receptors that contribute to lowly feelings of depression.

I was so excited to try this but it hasn’t helped my back pain whatsoever. I’ve been taking it for 2 months and I’m going to give it one more month. I am taking the 500 and have doubled the dose making it 1000 mg. So disappointed.I thought in the beginning that it was giving me a little more energy. Maybe it has. I love the company. It is so easy to order and it’s shipped right away.
Hempseed oil comes from the seeds of select species of Cannabis. These are tall growing and have low concentration of THC. Hemp trees have been used since ancient times to produce cloth and paper. Hemp fibers have good strength, both in tension and shear. Ropes made with hemp fibers have incredible strength.  It is also used to produce the oil. Its seeds have been used as food, mainly for animals.
A: We offer two different hemp products. First we have our Virgin Cannabis Sativa Hemp Oil. Our Virgin hemp oil comes from the seeds of the hemp plant. The seeds of the hemp plant contain only trace amounts of cannabinoids. Our Virgin hemp oil is a nutritional oil rich in vegan omegas. Our 3rd party lab test do not show any levels of cannabinoids. 
LEGAL NOTICES: Care By Design products have not been evaluated by the Food and Drug Administration (FDA). This information is not intended to diagnose, treat or cure any disease. This information should not be interpreted as medical advice or treatment. You should consult your physician or other health care professional before starting any medication or supplements. Further, Care By Design does not manufacture, sell or distribute any products that are in violation of California State Law.
The bad news: CBD, just like any other supplement sold in the U.S., isn’t regulated. That means you can never be totally sure of the amount of CBD you’re getting. “If you and I go into a local cannabis shop, even a shop with a lot of experience of people coming in for medical reasons—unless you’re in Canada or Netherlands, where they have federally-produced drugs—we can’t trust that what’s on the label is what we’re actually getting,” Craft says. That means you could be getting more or less of CBD, as well as THC (which has its own set of side effects).
In general, the majority of people end up using higher-strength products for pain than they would for things like anxiety, stress, or depression. The majority of today’s best CBD oil manufacturers offer tinctures in three different “potencies,” usually in 100, 300, or 600 mg options. Many people start on a middle ground with a 300 mg option, and work your way up from there, but it is extremely important to consult with the brand you are purchasing from before consumption.

I was so excited to try this but it hasn’t helped my back pain whatsoever. I’ve been taking it for 2 months and I’m going to give it one more month. I am taking the 500 and have doubled the dose making it 1000 mg. So disappointed.I thought in the beginning that it was giving me a little more energy. Maybe it has. I love the company. It is so easy to order and it’s shipped right away.


Although THC is best known for its mind-altering euphoria, it too has important medical benefits. There’s some overlap in what CBD and THC can treat, but THC is particularly effective in relieving nausea, appetite loss, insomnia, among other symptoms. Many patients find that a balance of CBD and THC offers the best symptom relief as the two work together synergistically.
Perhaps this is what’s behind the government’s wicked, senseless plan with the opioid crisis; to legalize marijuana. If you ask me I think marijuana should have been legalized years ago and alcohol outlawed. I don’t use either one but I’ve seen what alcohol can do to someone versus pot. I also think that those of us who want to take our medication with a glass of water, wait an hour and have hours of relief should not be forced to stop it and start smoking pot either. When it comes to one’s health there should be a choice for everyone involved. If you want to smoke your pain medicine being marijuana then do it; if you want to continue taking your opioid medicine that you KNOW helps then do it. This whole thing has gotten completely out of hand and is totally ridiculous! Then again it doesn’t matter what I think or for that fact any of us. The government’s going to do what the government wants to do and no one but no one can change this, not here on earth anyway. I still have to stop and wonder if every single doctor in America would have stood up and fought this when it first began where we would ALL be now. I’ll never forget our veteran, Mr. Robert Rose. He fought in a battle to save our country. He comes back and has to fight another battle of a different kind. The government wouldn’t even give the man 11 minutes for the 11 years he served his country.. He “finally” got his chance to speak,( I think due to many prayers being said for him.)His bravery then took him to court in Greeneville Tennessee where the “fine governor” of Tennessee, Dr. Phil Roe WOULD NOT even make an appearance! Mr. Robert Rose chose bravery in action more times than once. Governor Phil Roe and the rest of them choose to HIDE behind their desks, continuing to run their mouths and just look at the shape it’s gotten us all in. Whether it’s marijuana, opioids, suicide, turning to alcohol, etc. I reckon where there’s a will; we’ll find a way…..

Other potential side effects include low blood pressure, lightheadedness, and drowsiness, but these have typically only occurred in patients who have exceeded doses of 1,500 mg daily for a period of 4 weeks or more; far more than the average person will need take on a daily basis for chronic pain symptoms. (In fact, the majority of CBD users claim they find an effective dose to be anywhere between 10 and 40 mg daily).
Concerns are frequently noted with new drug-drug interactions, but few have resulted in Sativex RCTs despite its adjunctive use with opiates, many other psychoactive analgesic, antidepressant and anticonvulsant drugs (Russo 2006a), possibly due to CBD ability to counteract sedative effects of THC (Nicholson et al 2004). No effects of THC extract, CBD extract or Sativex were observed in a study of effects on the hepatic cytochrome P450 complex (Stott et al 2005b). On additional study, at 314 ng/ml cannabinoid concentration, Sativex and components produced no significant induction on human CYP450 (Stott et al 2007). Thus, Sativex should be safe to use in conjunction with other drugs metabolized via this pathway.
What a great article on CBD oils which only touches the surface of its benefits!! Only thing I disagree upon is it mentions CBD not containing any psychotropics. CBD oil requires a touch of THC to properly work. If the solution is strong enough and people take more than necessary one can get s little “high” for reals. A tiny amount of CBD oil goes a long way, especially when you have the oils directly produced from squeezing the oils from CBD prominent plants. Sativa plants often have a higher THC component than Indica plants and Sativa plants are smoked for their “get up and go properties “ rather than the more relaxing kick back Indica plants
This non-greasy formula is a lightweight counterpart to all those heavy hemp salves and balms that you tend to see on the market, so much so that you could use this every day on your entire body without worries about staining your clothes. Along with the Colorado-grown CBD oil, it has a lotion base made with aloe vera leaf juice powder (good for antioxidants), lactic acid (good for exfoliation), and other reputable skincare ingredients. Keep this by your shower and use it while your skin is still moist, warm, and soft for the best results.

As one of the original CBD manufacturers, Green Roads reputation truly precedes them, and their pharmacist formulated manufacturing process is why we selected them as the best quality CBD oil on the market. They offer a range of CBD oil concentrations (100mg, 250mg, 350mg, 550mg, 1000mg, 1500mg, and 3,500mg) all of which allow you to view ingredients and test results from a 3rd party testing facility via a QR code on the box.
While in all of these states recreational marijuana remains illegal, Connecticut, Delaware, Illinois, Maryland, Minnesota, Mississippi, Missouri, Nebraska, New Hampshire, New York, North Carolina, Ohio and Rhode Island have all decriminalized the drug. In these states, having smaller amounts of marijuana on you won't lead to an arrest or a criminal record. The maximum amount you're allowed to have on your person will vary by state.
In a report published in Pediatric Dermatology in 2018, scientists reported three cases of topical CBD (applied as an oil, cream, and spray) use in children with a rare, blistering skin condition known as epidermolysis bullosa. Applied by their parents, all three people reported faster wound healing, less blisters, and improvement of pain. One person was able to completely wean off oral opioid analgesic pain medication. There were no adverse effects reported.
Endocannabinoids are organically produced by the human body, generated by the endocannabinoid system. Endocannabinoids have been found to help in the regulation of sleep, pain and the responses of the immune system. Cannabis scientists have been investigating the role of physiological cannabinoids in tissue recovery and disease. It is fascinating that the endocannabinoids activate the same receptors as the psychoactive THC.

Computers by Design, Inc (CBD) has announced the release of CBD True Data Cybrarian, a Windows front-end interface designed for the needs of libraries it offers administrators a wealth of security features, according to CBD It provides security for public access computers, monitors and reports on patron usage, sets session time limits, and authenticates users CBD reports that True Data Cybrarian system guards against malicious hacks or accidental system modifications, but grants full access to all authorized software It can track over 650,000 programs on every desktop, and each desktop can be individually configured or grouped into specialty contigurations The cost for True Data Cybrarian is $1,295 for an unlimited-user site license.
The degree to which cannabinoid analgesics will be adopted into adjunctive pain management practices currently remains to be determined. Data on Sativex use in Canada for the last reported 6-month period (January-July 2007) indicated that 81% of prescriptions issued for patients in that interval were refills (data on file, from Brogan Inc Rx Dynamics), thus indicating in some degree an acceptance of, and a desire to, continue such treatment. Given their multi-modality effects upon various nociceptive pathways, their adjunctive side benefits, the efficacy and safety profiles to date of specific preparations in advanced clinical trials, and the complementary mechanisms and advantages of their combination with opioid therapy, the future for cannabinoid therapeutics appears very bright, indeed.
Kent, My mother has suffered from severe migraines since she was a child. Six weeks ago, she received the hemp oil tincture (I do not know what dosage). She does not take it daily. She rubs a drop or two on her temples at the start of a migraine. The drops worked more effectively for her than her medication did, and now that is all she uses. Hope this helps.

I have lower back pain with some arthritis and arthritis in my hands.ive recently tried CBD Oil. It really does work. I have the drops and ointment. They both work. Because of the back pain I never would have been able to go on a hike with my family. We had a lot of fun. And "No Pain", all day. I'm also Type 2 diabetic. Anxious to see what my A1C is next month. I'm a believer.


Sativex® (GW Pharmaceuticals) is an oromucosal whole cannabis-based spray combining a CB1 partial agonist (THC) with a cannabinoid system modulator (CBD), minor cannabinoids and terpenoids plus ethanol and propylene glycol excipients and peppermint flavoring (McPartland and Russo 2001; Russo and Guy 2006). It was approved by Health Canada in June 2005 for prescription for central neuropathic pain in multiple sclerosis, and in August 2007, it was additionally approved for treatment of cancer pain unresponsive to optimized opioid therapy. Sativex is a highly standardized pharmaceutical product derived from two Cannabis sativa chemovars following Good Agricultural Practice (GAP) (de Meijer 2004), yielding Tetranabinex® (predominantly-THC extract) and Nabidiolex® (predominantly-CBD extract) in a 1:1 ratio. Each 100 μL pump-action oromucosal Sativex spray actuation provides 2.7 mg of THC and 2.5 mg of CBD. Pharmacokinetic data are available, and indicate plasma half lives of 85 minutes for THC, 130 minutes for 11-hydroxy-THC and 100 minutes for CBD (Guy and Robson 2003). Sativex effects commence in 15–40 minutes, an interval that permits symptomatic dose titration. A very favorable adverse event profile has been observed in over 2500 patient years of exposure in over 2000 experimental subjects. Patients most often ascertain an individual stable dosage within 7–10 days that provides therapeutic relief without unwanted psychotropic effects (often in the range of 8–10 sprays per day). In all RCTs, Sativex was adjunctively added to optimal drug regimens in subjects with intractable symptoms, those often termed “untreatable.” Sativex is also available by named patient prescription in the UK and the Catalonia region of Spain. An Investigational New Drug (IND) application to study Sativex in advanced clinical trials in the USA was approved by the FDA in January 2006 in patients with intractable cancer pain.
^ Jump up to: a b Resstel LB, Tavares RF, Lisboa SF, Joca SR, Corrêa FM, Guimarães FS (January 2009). "5-HT1A receptors are involved in the cannabidiol-induced attenuation of behavioural and cardiovascular responses to acute restraint stress in rats". British Journal of Pharmacology. 156 (1): 181–8. doi:10.1111/j.1476-5381.2008.00046.x. PMC 2697769. PMID 19133999.
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