Of the many developmental disorders, autism and its associated spectrum of disorders are perhaps the most pervasive. Autistic children suffer from insomnia, irritability and a loss of appetite, to name a few. Practitioners have been experimenting with the use of CBD oil in curtailing the social anxiety and psychological manifestations vicariously caused in victims of autism.
Like other cannabinoids, CBD readily crosses the blood brain barrier, making it ideal for affecting central nervous system conditions. CBD helps calm the nervous system, reduces inflammation, and is strongly neuroprotective. Not surprisingly, clinical studies evaluating cannabidiol for treatment of anxiety, post traumatic stress disorder (PTSD), seizure disorders (especially childhood seizures), and even schizophrenia have shown remarkable effectiveness.
In general, the majority of people end up using higher-strength products for pain than they would for things like anxiety, stress, or depression. The majority of today’s best CBD oil manufacturers offer tinctures in three different “potencies,” usually in 100, 300, or 600 mg options. Many people start on a middle ground with a 300 mg option, and work your way up from there, but it is extremely important to consult with the brand you are purchasing from before consumption.
"Cannabinoids have been found to have antioxidant properties, unrelated to NMDA receptor antagonism. This new found property makes cannabinoids useful in the treatment and prophylaxis of wide variety of oxidation associated diseases, such as ischemic, age-related, inflammatory and autoimmune diseases. The cannabinoids are found to have particular application as neuroprotectants, for example in limiting neurological damage following ischemic insults, such as stroke and trauma, or in the treatment of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease and HIV dementia.
Over the past few decades, most strains have been bred to increase the amount of the main psychoactive component, (-)-trans-delta9-tetrahydrocannabinol (THC). However, within the past decade, researchers have become increasingly interested in the medical benefits of another compound found in both plants, known as cannabidiol (CBD). CBD is a non-psychoactive component of the cannabis plant but is reputed to help with a myriad of medical conditions.
This is great news for hemp farmers and consumers interested in CBD, an industry that’s predicted to hit $22 billion by 2022. However, the CBD market has all the makings of a wild west show, with many businesses anxious to get in on the action and make a tidy profit. As such, you’re likely to see CBD-infused products with prices all over the map. And with no official system of checks and balances, it will be hard to tell how much CBD is actually present or what quality it is.
While there are more unknowns than knowns at this point, Grant says he doesn’t discount all the anecdotal CBD reports. “You hear somebody say, ‘Hey, I gave this to myself and my kid and we feel a lot better,’ and we should never dismiss that kind of information,” he says. He points out that many modern medicines were discovered when researchers followed up on exactly this sort of human trial-and-error evidence. “But we still need to do the studies that confirm whether all the good things are true, and how much to give, and how to give it,” he says. “These are all questions that need to be answered.”
CBD has proven neuroprotective effects and its anti-cancer properties are being investigated at several academic research centers in the United States and elsewhere. A 2010 brain cancer study by California scientists found that CBD “enhances the inhibitory effects of THC on human glioblastoma cell proliferation and survival.” This means that CBD makes THC even more potent as an anticancer substance. Also in 2010, German researchers reported that CBD stimulates neurogenesis, the growth of new brain cells, in adult mammals.
CBD from Industrial Hemp Plants that contain Cannabinoids. You cannot experience any psychoactive effects “High or Stoned” with our products. They all contain less than .3% THC or 0% THC. Every major civilization in history has recognized hemp as #1 on its list of important plants. The ancient Chinese, Indians, Egyptians, Assyrians, Persians, Greeks and Romans all revered hemp as an excellent source of food and medicine. Now modern science is validating what the ancients all knew — and uncovering exciting discoveries about CBD. Recently (August 2017) FDA has declared CBD as “beneficial” and is asking now all users of CBD products for their input.
Compared to THC, CBD has very different properties. It weakly binds to both CB1 and CB2 receptors in the brain and body, gently stimulating and blocking them at the same time. This not only mildly activates the receptors, but is also thought to trigger the body to create more CB1 and CB2 receptors, a process known as upregulation. It also results in increased natural levels of anandamide.
Under federal law, cannabis (from which both CBD and marijuana are derived) is illegal everywhere, although the laws against it aren’t generally enforced in states that have legalized marijuana. Some manufacturers claim that CBD culled from legally imported industrial hemp, which has little to no THC, is fine to ship across the U.S., but many experts disagree, noting that because hemp comes from the same species as marijuana, cannabis sativa, all CBD falls under the DEA’s Schedule 1 designation. “This creative interpretation of the law runs afoul of reality,” says the Brookings Institution, a Washington, DC, think tank.